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The subject of the study are theoretical and applied aspects of the implementation of fundamental R&D (FR&D), the essence of which is the constant expansion of resources of social consumption and the formation of high-risk sources of increasing the level of collective well-being; promoting consolidated and sustainable development; management of the design and structure of a complex of unprocessed assets of national wealth, produced by real sector of national economy goods / services provided by social sector of national economy, material and intangible values with a high potential of value added production; formation of high-tech services based on the use of basic concepts and satisfaction of consumer expectations in them; development of logically justified formatin of fundamental science theoryn, renewal and use of fundamental science knowledge, concepts and sensual-figurative models of the world’ science picture with opportunities for further use in public practice; increasing the level of trust and reciprocity, improving the physical and psychological well-being of members of network communities by setting up relations of understanding and mutual support of carriers of values of social and scientific capital – participants in the processes of forming the intellectual potential of local social networks of institutional agents of the post-industrial knowledge economy. The research method is to summarize the theoretical and applied aspects of the modern stage of FR&D’ implementation in cognitive society, which is associated with a critical analysis of the results of theoretical research in the field of gnoseology, as well as the study of features of the implementation of applied theories of changing the scientific paradigms of leading scientists of our time. The result of the study is the formation of an integrated approach to the implementation FR&D in the context of a direct transition to the post-industrial knowledge economy. The definition of the need for the implementation of FR&D as an emotional state capable of creative social group of research scientists and society as a whole is formulated, which expresses dependence on the objective content of conditions of existence and development and acts as a source of various forms of activity in the public interest. The potential of FR&’ implementation is defined as the ability to intensify the processes of purposeful, costly, long-term nonlinear, multi-stage and cumulative learning, which leads to interactive, technologically specialized and culturally determined constant innovation activities of research universities with the subsequent receipt of market advantages.